Oct 24, 2009: GENDIA now offers a next-generation sequencing  platform for the molecular diagnosis of Usher Syndrome with complete sequencing of all 9 Usher genes:

USHER TYPE 1

• MYO7A encoding Myosin 7A for Usher syndrome type 1A/B (USH1A/B)
• USH1C encoding Harmonin for Usher syndrome type 1C (USH1C)
• CDH23  encoding Cadherin23 for Usher syndrome type 1D (USH1D)
• PCDH15 encoding Protocadherin15 for Usher syndrome type 1F (USH1F)
• USH1G encoding Usher syndrome type-1G protein for Usher syndrome type 1G (USH1G)

USHER TYPE 2

• USH2A encoding Usherin for Usher syndrome type 2A (USH2A)
• GPR98 (exons 8, 20, 31-41 & 89) encoding  the G-protein-coupled 7-transmem-brane receptor  for for Usher syndrome type 2C (USH2C)
• WHRN encoding Whirlin for Usher syndrome type 2D (USH2D)

USHER TYPE 3

• CLRN1 encoding Clarin 1 for Usher syndrome type 3A (USH3A)

This platform also offers a molecular diagnosis of Non-Syndromic Deafness with sequencing of the following 10 genes:

• GJB6
• MYO6
• OTOF
• SLC26A4 (PDS)
• TMC1
• TMIE
• TMPRSS3
• TMC1
• MTTS (tRNAser(UCN))
• MTRNR1 (6 mutations in 12S rRNA)