Oct 30, 2009: GENDIA now offers a next-generation sequencing  platform for the molecular diagnosis of Familial Cardiomyopathy.
This platform is directly sequencing single DNA molecules with the Helicos' True Single Molecule Sequencing (tSMS)™ technology.
The platform detects mutations in:

> 65% of Hypertrophic Cardiomyopathy (HCM)
> 40% of Dilated Cardiomyopathy (DCM)
> 50% of Arrhythmogenic Right Ventricular Dysplasia (ARVD) / Cardiomyopathy
> 10% of other Cardiomyopathies (restrictive, left ventricular non-compaction)

with sequencing of the following 57 genes:

• ABCC9 gene encoding ATP-binding cassette, subfamily c, member 9
• ACTC1 gene encoding cardiac actin
• ACTN2 gene encoding actinin, alpha-2, ALMS1 gene encoding Alstrom syndrome protein
• APOA1 gene encoding apolipoprotein A1
• CAV3 gene encoding caveolin 3
• CSRP3 gene encoding cysteine- and glycine-rich protein 3
• CTF1 gene encoding cardiotrophin
• DES gene encoding desmin
• DNAJC19 gene encoding DNAJ/HSP40 homolog, subfamily c, member 19
• DSC2 gene encoding desmocollin-2
• DSG2 gene encoding desmoglein-2
• DSP gene encoding desmoplakin
• DTNA gene encoding dystrobrevin, alpha
• EMD gene encoding emerin
• FKTN gene encoding fukutin
• GLA gene encoding alpha galactosidase
• HOPX gene encoding hop homeobox
• JUP gene encoding junction plakoglobin
• LAMP2 gene encoding lysosome-associated membrane protein 2
• LDB3 gene encoding lim domain-binding 3
• LMNA gene encoding lamin A/C
• MTND1, MTND5, and MTND6 gene encoding 3 Mitochondrial complex 1 subunits ND1, ND5 and ND6
• MTTG, MTTI, MTTL1, MTTQ, MTTH, MTTK, MTTS1 and MTTS2 gene encoding 8 Mitochondrial transfer RNAs
• MYBPC3 gene encoding myosin-binding protein C
• MYH6 gene encoding myosin heavy chain 6
• MYH7 gene encoding myosin heavy chain 7
• MYL2 gene encoding myosin, light chain 2
• MYL3 gene encoding myosin, light chain 3
• MYLK2 gene encoding myosin light chain kinase 2
• PKP2 gene encoding plakophilin-2
• PLN gene encoding phospholamban
• PRKAG2 gene encoding noncatalytic AMP-activated protein kinase gamma 2
• RYR2 gene encoding ryanodine receptor 2
• SCN5A gene encoding sodium channel, voltage-gated, type v, alpha subunit
• SGCD gene encoding delta-sarcoglycan
• TAZ gene encoding tafazzin
• TCAP gene encoding titin-cap
• TGFB3 gene encoding transforming growth factor, beta-3
• TMEM43 gene encoding transmembrane protein 43
• TMPO gene encoding thymopoietin
• TNNC1 gene encoding troponin C
• TNNI3 gene encoding troponin I
• TNNT2 gene encoding troponin T
• TPM1 gene encoding tropomyosin 1
• TTN gene encoding titin
• TTR gene encoding transthyretin
• VCL gene encoding vinculin